| Reaction Details |
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 | Report a problem with these data |
| Target | Collagenase ColA |
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| Ligand | BDBM50100809 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_49485 (CHEMBL659907) |
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| Ki | 19±n/a nM |
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| Citation |  Clare, BW; Scozzafava, A; Supuran, CT Protease inhibitors: synthesis of a series of bacterial collagenase inhibitors of the sulfonyl amino acyl hydroxamate type. J Med Chem44:2253-8 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Collagenase ColA |
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| Name: | Collagenase ColA |
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| Synonyms: | 120 kDa collagenase | COLA_CLOPE | Microbial collagenase | colA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 125901.02 |
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| Organism: | Clostridium perfringens |
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| Description: | ChEMBL_49485 |
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| Residue: | 1104 |
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| Sequence: | MKKNLKRGELTKLKLVERWSATFTLAAFILFNSSFKVLAADKKVENSNNGQITREINADQ
ISKTELNNEVATDNNRPLGPSIAPSRARNNKIYTFDELNRMNYSDLVELIKTISYENVPD
LFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTYTADDDKGIPTLVEFLRAGYYLGFYNKQL
SYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQDGVVEALGRLIGNASADPEVINNCIYVL
SDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTNSVIYNTKGYDAKNTEFYNRIDPYMERLE
SLCTIGDKLNNDNAWLVNNALYYTGRMGKFREDPSISQRALERAMKEYPYLSYQYIEAAN
DLDLNFGGKNSSGNDIDFNKIKADAREKYLPKTYTFDDGKFVVKAGDKVTEEKIKRLYWA
SKEVKAQFMRVVQNDKALEEGNPDDILTVVIYNSPEEYKLNRIINGFSTDNGGIYIENIG
TFFTYERTPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAEFF
AGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYGSWDFYNYGFALSNYMYNNNMGM
FNKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSLLNNIDNLDVPLVSDEYVNGH
EAKDINEITNDIKEVSNIKDLSSNVEKSQFFTTYDMRGTYVGGRSQGEENDWKDMNSKLN
DILKELSKKSWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIK
SDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVT
DNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYY
FDVAKKGNVKITLNNLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKGEKTLEPGRYYLS
VYTYDNQSGTYTVNVKGNLKNEVKETAKDAIKEVENNNDFDKAMKVDSNSKIVGTLSNDD
LKDIYSIDIQNPSDLNIVVENLDNIKMNWLLYSADDLSNYVDYANADGNKLSNTCKLNPG
KYYLCVYQFENSGTGNYIVNLQNK
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| BDBM50100809 |
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| n/a |
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| Name | BDBM50100809 |
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| Synonyms: | 2-(N-(2-nitrobenzyl)-4-methoxyphenylsulfonamido)-N-hydroxypropanamide | CHEMBL450327 | N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-(2-nitro-benzyl)-amino]-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H19N3O7S |
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| Mol. Mass. | 409.414 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1[N+]([O-])=O)C(C)C(=O)NO |
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| Structure | 
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