Ki Summary

Reaction Details

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Target

Carnitine O-palmitoyltransferase 1, muscle isoform

Ligand

BDBM50101604

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_46323 (CHEMBL660891)

IC50

>10000±n/a nM

Citation

Giannessi, F; Chiodi, P; Marzi, M; Minetti, P; Pessotto, P; De Angelis, F; Tassoni, E; Conti, R; Giorgi, F; Mabilia, M; Dell'Uomo, N; Muck, S; Tinti, MO; Carminati, P; Arduini, A Reversible carnitine palmitoyltransferase inhibitors with broad chemical diversity as potential antidiabetic agents. J Med Chem44:2383-6 (2001) [PubMed]

More Info.:

Get all data from this article, Assay Method

Carnitine O-palmitoyltransferase 1, muscle isoform

Name:

Carnitine O-palmitoyltransferase 1, muscle isoform

Synonyms:

CPT1B_RAT | Carnitine palmitoyltransferase 1B | Cpt1b

Type:

PROTEIN

Mol. Mass.:

88241.28

Organism:

Rattus norvegicus

Description:

ChEMBL_887447

Residue:

772

Sequence:

MAEAHQAVAFQFTVTPDGVDFRLSREALRHIYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVVMATVGSNYCKVDISMGLVHCIQRCLPTRYGSYGTPQTETLLSMVIFSTGVWATG
IFLFRQTLKLLLSYHGWMFEMHSKTSHATKIWAICVRLLSSRRPMLYSFQTSLPKLPVPS
VPATIHRYLDSVRPLLDDEAYFRMESLAKEFQDKIAPRLQKYLVLKSWWATNYVSDWWEE
YVYLRGRSPIMVNSNYYAMDFVLIKNTSQQAARLGNTVHAMIMYRRKLDREEIKPVMALG
MVPMCSYQMERMFNTTRIPGKETDLLQHLSESRHVAVYHKGRFFKVWLYEGSCLLKPRDL
EMQFQRILDDTSPPQPGEEKLAALTAGGRVEWAEARQKFFSSGKNKMSLDTIERAAFFVA
LDEDSHCYNPDDEASLSLYGKSLLHGNCYNRWFDKSFTLISCKNGQLGLNTEHSWADAPI
IGHLWEFVLATDTFHLGYTETGHCVGEPNTKLPPPQRMQWDIPEQCQTAIENSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDKGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVRAMMTGSHKKQDLQDLFRKASEKHQNMYRLAMTGAGIDRHLFCL
YIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQFQICMFDPKQYPNHLGAGGGFGPVADHGY
GVSYMIAGENTMFFHVSSKLSSSETNALRFGNHIRQALLDIADLFKISKTDS

BDBM50101604

n/a

Name

BDBM50101604

Synonyms:

CHEMBL309568 | [3-Carboxy-2-(dodecane-1-sulfonylamino)-propyl]-trimethyl-ammonium

Type

Small organic molecule

Emp. Form.

C19H40N2O4S

Mol. Mass.

392.597

SMILES

CCCCCCCCCCCCS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C

Structure