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TargetProstaglandin E2 receptor EP3 subtype
LigandBDBM50101823
Substrate/Competitorn/a
Meas. Tech.ChEBML_158323
Ki>0.000100±n/a nM
Citation Tani, KNaganawa, AIshida, AEgashira, HSagawa, KHarada, HOgawa, MMaruyama, TOhuchida, SNakai, HKondo, KToda, M Design and synthesis of a highly selective EP2-receptor agonist. Bioorg Med Chem Lett11:2025-8 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP3 subtype
Name:Prostaglandin E2 receptor EP3 subtype
Synonyms:PE2R3_MOUSE | PGE receptor, EP3 isoform alpha | Prostaglandin E2 receptor EP3 isoform alpha | Prostaglandin E3 | Prostanoid EP3 receptor | Ptger3 | Ptgerep3
Type:G-protein coupled receptor
Mol. Mass.:40092.50
Organism:Mus musculus (Mouse)
Description:n/a
Residue:365
Sequence:
MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESK
RKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLS
SLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWP
GTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKA
AVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKE
CNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWS
DQLER
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50101823
n/a
NameBDBM50101823
Synonyms:4-(2-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1-propyl-cyclobutyl)-but-1-enyl]-5-oxo-cyclopentyl}-ethyl)-benzoic acid | CHEMBL64423
TypeSmall organic molecule
Emp. Form.C25H34O5
Mol. Mass.414.5345
SMILESCCCC1(CCC1)[C@@H](O)C\C=C\C1[C@H](O)CC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O
Structure
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