Reaction Details |
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Target | Prostaglandin E2 receptor EP3 subtype |
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Ligand | BDBM50101863 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_158325 |
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Ki | 3.7±n/a nM |
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Citation | Maruyama, T; Asada, M; Shiraishi, T; Sakata, K; Seki, A; Yoshida, H; Shinagawa, Y; Maruyama, T; Ohuchida, S; Nakai, H; Kondo, K; Toda, M Design and synthesis of a highly selective EP4-receptor agonist. Part 2: 5-thia and 9beta-haloPG derivatives with improved stability. Bioorg Med Chem Lett11:2033-5 (2001) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Prostaglandin E2 receptor EP3 subtype |
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Name: | Prostaglandin E2 receptor EP3 subtype |
Synonyms: | PE2R3_MOUSE | PGE receptor, EP3 isoform alpha | Prostaglandin E2 receptor EP3 isoform alpha | Prostaglandin E3 | Prostanoid EP3 receptor | Ptger3 | Ptgerep3 |
Type: | G-protein coupled receptor |
Mol. Mass.: | 40092.50 |
Organism: | Mus musculus (Mouse) |
Description: | n/a |
Residue: | 365 |
Sequence: | MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESK
RKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLS
SLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWP
GTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKA
AVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKE
CNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWS
DQLER
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BDBM50101863 |
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n/a |
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Name | BDBM50101863 |
Synonyms: | 3-{(S)-3-[(R)-3-Hydroxy-2-((1R,2R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentyl]-propylsulfanyl}-propionic acid | CHEMBL62868 |
Type | Small organic molecule |
Emp. Form. | C19H32O5S |
Mol. Mass. | 372.519 |
SMILES | CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCSCCC(O)=O |
Structure |
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