| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 1 |
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| Ligand | BDBM50064801 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_147547 (CHEMBL754874) |
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| IC50 | 10200±n/a nM |
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| Citation |  Kim, YC; Brown, SG; Harden, TK; Boyer, JL; Dubyak, G; King, BF; Burnstock, G; Jacobson, KA Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. J Med Chem44:340-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 1 |
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| Name: | P2X purinoceptor 1 |
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| Synonyms: | ATP receptor | P2RX1_RAT | P2X1 | P2rx1 | Purinergic receptor | Purinergic, P2X1 | RP-2 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44969.95 |
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| Organism: | RAT |
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| Description: | Purinergic, P2X1 0 RAT::P47824 |
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| Residue: | 399 |
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| Sequence: | MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSD
LISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIVTPQQTQGHCAEN
PEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKIQHPLCPVFNLGYVVRESG
QDFRSLAEKGGVVGITIDWKCDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQN
GTNRRHLFKVFGIHFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGEGEHDPVATSSTLGLQENMRTS
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| BDBM50064801 |
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| n/a |
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| Name | BDBM50064801 |
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| Synonyms: | 2-(4,7-Dihydroxy-3-methyl-7-oxo-5,9-dihydro-6,8-dioxa-2-aza-7lambda*5*-phospha-benzocyclohepten-1-ylazo)-benzene-1,4-disulfonic acid | CHEMBL304765 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N3O11PS2 |
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| Mol. Mass. | 495.378 |
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| SMILES | Cc1nc(N=Nc2cc(ccc2S(O)(=O)=O)S(O)(=O)=O)c2COP(O)(=O)OCc2c1O |w:4.3| |
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| Structure | 
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