| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2X purinoceptor 3 |
|---|
| Ligand | BDBM50102298 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_147552 (CHEMBL751122) |
|---|
| IC50 | 128±n/a nM |
|---|
| Citation |  Kim, YC; Brown, SG; Harden, TK; Boyer, JL; Dubyak, G; King, BF; Burnstock, G; Jacobson, KA Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. J Med Chem44:340-9 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2X purinoceptor 3 |
|---|
| Name: | P2X purinoceptor 3 |
|---|
| Synonyms: | ATP receptor | P2RX3_RAT | P2X purinoceptor 3 | P2X3 | P2rx3 | Purinergic receptor | ratp2x3 | ratp2x3 + rsa |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44397.63 |
|---|
| Organism: | RAT |
|---|
| Description: | Purinergic, P2X3 0 RAT::P49654 |
|---|
| Residue: | 397 |
|---|
| Sequence: | MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSV
VTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDS
QCGPERFPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIR
FPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLG
IKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKA
FGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEE
VTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH
|
|
|
|---|
| BDBM50102298 |
|---|
| n/a |
|---|
| Name | BDBM50102298 |
|---|
| Synonyms: | 4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-pyridin-2-ylazo)-benzoic acid | CHEMBL119180 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H14N3O7P |
|---|
| Mol. Mass. | 379.2613 |
|---|
| SMILES | Cc1nc(N=Nc2ccc(cc2)C(O)=O)c(CP(O)(O)=O)c(C=O)c1O |w:5.5| |
|---|
| Structure | 
|
|---|
Search and Browse
