| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 2 |
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| Ligand | BDBM50102299 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_147550 (CHEMBL754947) |
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| IC50 | 280±n/a nM |
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| Citation |  Kim, YC; Brown, SG; Harden, TK; Boyer, JL; Dubyak, G; King, BF; Burnstock, G; Jacobson, KA Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. J Med Chem44:340-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 2 |
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| Name: | P2X purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RX2_RAT | P2X purinoceptor 2 | P2X2 | P2X2/P2X3 receptor | P2rx2 | Purinergic receptor | Purinergic, P2X2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52625.55 |
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| Organism: | RAT |
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| Description: | Purinergic, P2X2 0 RAT::P49653 |
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| Residue: | 472 |
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| Sequence: | MVRRLARGCWSAFWDYETPKVIVVRNRRLGFVHRMVQLLILLYFVWYVFIVQKSYQDSET
GPESSIITKVKGITMSEDKVWDVEEYVKPPEGGSVVSIITRIEVTPSQTLGTCPESMRVH
SSTCHSDDDCIAGQLDMQGNGIRTGHCVPYYHGDSKTCEVSAWCPVEDGTSDNHFLGKMA
PNFTILIKNSIHYPKFKFSKGNIASQKSDYLKHCTFDQDSDPYCPIFRLGFIVEKAGENF
TELAHKGGVIGVIINWNCDLDLSESECNPKYSFRRLDPKYDPASSGYNFRFAKYYKINGT
TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSIGVGSFLCDWILLTFMNKNK
LYSHKKFDKVRTPKHPSSRWPVTLALVLGQIPPPPSHYSQDQPPSPPSGEGPTLGEGAEL
PLAVQSPRPCSISALTEQVVDTLGQHMGQRPPVPEPSQQDSTSTDPKGLAQL
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| BDBM50102299 |
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| n/a |
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| Name | BDBM50102299 |
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| Synonyms: | 2-(4-Formyl-5-hydroxy-6-methyl-3-phosphonomethyl-pyridin-2-ylazo)-benzene-1,4-disulfonic acid | CHEMBL119416 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N3O11PS2 |
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| Mol. Mass. | 495.378 |
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| SMILES | Cc1nc(N=Nc2cc(ccc2S(O)(=O)=O)S(O)(=O)=O)c(CP(O)(O)=O)c(C=O)c1O |w:4.3| |
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| Structure | 
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