| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 4 |
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| Ligand | BDBM85043 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_147556 (CHEMBL751126) |
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| IC50 | 2600±n/a nM |
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| Citation |  Kim, YC; Brown, SG; Harden, TK; Boyer, JL; Dubyak, G; King, BF; Burnstock, G; Jacobson, KA Structure-activity relationships of pyridoxal phosphate derivatives as potent and selective antagonists of P2X1 receptors. J Med Chem44:340-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 4 |
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| Name: | P2X purinoceptor 4 |
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| Synonyms: | P2RX4_RAT | P2rx4 | Purinergic, P2X4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43504.16 |
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| Organism: | RAT |
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| Description: | Purinergic, P2X4 0 RAT::P51577 |
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| Residue: | 388 |
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| Sequence: | MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIP
DKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAG
HSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYY
RDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYC
MKKKYYYRDKKYKYVEDYEQGLSGEMNQ
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| BDBM85043 |
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| n/a |
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| Name | BDBM85043 |
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| Synonyms: | CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPADS |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N3O12PS2 |
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| Mol. Mass. | 511.378 |
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| SMILES | Cc1nc(N=Nc2ccc(cc2S(O)(=O)=O)S(O)(=O)=O)c(COP(O)(O)=O)c(C=O)c1O |w:4.3| |
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| Structure | 
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