| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1E |
|---|
| Ligand | BDBM50091438 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2070 (CHEMBL616714) |
|---|
| Ki | 6.3±n/a nM |
|---|
| Citation |  Witherington, J; Bordas, V; Cooper, DG; Forbes, IT; Gribble, AD; Ife, RJ; Berkhout, T; Gohil, J; Groot, PH Conformationally restricted indolopiperidine derivatives as potent CCR2B receptor antagonists. Bioorg Med Chem Lett11:2177-80 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 1E |
|---|
| Name: | 5-hydroxytryptamine receptor 1E |
|---|
| Synonyms: | 5-HT-1E | 5-HT1E | 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) | 5-hydroxytryptamine receptor 1E | 5-hydroxytryptamine receptor 1E (5-HT-1E) (S31) | 5-hydroxytryptamine receptor 1E (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). | 5HT1E_HUMAN | HTR1E | S31 | Serotonin (5-HT) receptor | Serotonin 1e (5-HT1e) receptor | Serotonin Receptor 1E |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 41697.80 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_112822 |
|---|
| Residue: | 365 |
|---|
| Sequence: | MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYL
ICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDR
YWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHV
IYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQ
TFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAF
ILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIR
CREHT
|
|
|
|---|
| BDBM50091438 |
|---|
| n/a |
|---|
| Name | BDBM50091438 |
|---|
| Synonyms: | (E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-indol-3-yl)-piperidin-1-yl]-pentyl}-acrylamide | (E)-3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-indol-3-yl)piperidin-1-yl)pentyl)acrylamide | 3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-indol-3-yl)piperidin-1-yl)pentyl)acrylamide | CHEMBL432713 | TCMDC-139245 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H31Cl2N3O2 |
|---|
| Mol. Mass. | 500.46 |
|---|
| SMILES | Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
