| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50103839 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_61118 |
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| Ki | 0.470000±n/a nM |
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| Citation |  Feenstra, RW; de Moes, J; Hofma, JJ; Kling, H; Kuipers, W; Long, SK; Tulp, MT; van der Heyden, JA; Kruse, CG New 1-aryl-4-(biarylmethylene)piperazines as potential atypical antipsychotics sharing dopamine D(2)-receptor and serotonin 5-HT(1A)-receptor affinities. Bioorg Med Chem Lett11:2345-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50103839 |
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| n/a |
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| Name | BDBM50103839 |
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| Synonyms: | 7-{4-[4-(4-Fluoro-phenyl)-pyridin-2-ylmethyl]-piperazin-1-yl}-3H-benzooxazol-2-one | CHEMBL308345 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21FN4O2 |
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| Mol. Mass. | 404.4368 |
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| SMILES | Fc1ccc(cc1)-c1ccnc(CN2CCN(CC2)c2cccc3[nH]c(=O)oc23)c1 |
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| Structure | 
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