| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Aldehyde dehydrogenase, mitochondrial |
|---|
| Ligand | BDBM50104892 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_31176 (CHEMBL641141) |
|---|
| IC50 | 40±n/a nM |
|---|
| Citation |  Gao, GY; Li, DJ; Keung, WM Synthesis of potential antidipsotropic isoflavones: inhibitors of the mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway. J Med Chem44:3320-8 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Aldehyde dehydrogenase, mitochondrial |
|---|
| Name: | Aldehyde dehydrogenase, mitochondrial |
|---|
| Synonyms: | ALDH class 2 | ALDH-E2 | ALDH2 | ALDH2_HUMAN | ALDHI | ALDM | Aldehyde dehydrogenase (ALDH2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 56382.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P05091 |
|---|
| Residue: | 517 |
|---|
| Sequence: | MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPS
TGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLA
ALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCG
QIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPG
FGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADM
DWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGP
QVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGP
VMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQS
PFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
|
|
|
|---|
| BDBM50104892 |
|---|
| n/a |
|---|
| Name | BDBM50104892 |
|---|
| Synonyms: | 8-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)octanoic acid | 8-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-octanoic acid | CHEMBL114397 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H24O6 |
|---|
| Mol. Mass. | 396.4331 |
|---|
| SMILES | OC(=O)CCCCCCCOc1ccc2c(c1)occ(-c1ccc(O)cc1)c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
