| Reaction Details |
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 | Report a problem with these data |
| Target | Vascular cell adhesion protein 1 |
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| Ligand | BDBM50105156 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_213814 (CHEMBL819003) |
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| IC50 | 20±n/a nM |
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| Citation |  Zhu, GD; Arendsen, DL; Gunawardana, IW; Boyd, SA; Stewart, AO; Fry, DG; Cool, BL; Kifle, L; Schaefer, V; Meuth, J; Marsh, KC; Kempf-Grote, AJ; Kilgannon, P; Gallatin, WM; Okasinski, GF Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides. J Med Chem44:3469-87 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Vascular cell adhesion protein 1 |
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| Name: | Vascular cell adhesion protein 1 |
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| Synonyms: | CD106 antigen | INCAM-100 | VCAM-1 | VCAM1 | VCAM1_HUMAN | Vascular cell adhesion protein 1 | Vascular cell adhesion protein 1 (VCAM-1) | Vascular cell adhesion protein 1 precursor |
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| Type: | Other Protein Type |
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| Mol. Mass.: | 81259.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P19320 |
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| Residue: | 739 |
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| Sequence: | MPGKMVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWR
TQIDSPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPE
IHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEV
TFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGG
SVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKN
RKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVR
SEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGLVNGSS
VTVSCKVPSVYPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKA
LVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFP
APKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTP
KDIKLTAFPSESVKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQL
KDAGVYECESKNKVGSQLRSLTLDVQGRENNKDYFSPELLVLYFASSLIIPAIGMIIYFA
RKANMKGSYSLVEAQKSKV
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| BDBM50105156 |
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| n/a |
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| Name | BDBM50105156 |
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| Synonyms: | 4-{4-[2-(2-Methoxy-ethoxy)-ethoxymethyl]-phenoxy}-thieno[2,3-c]pyridine-2-carboxylic acid methylamide | CHEMBL117279 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24N2O5S |
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| Mol. Mass. | 416.491 |
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| SMILES | CNC(=O)c1cc2c(Oc3ccc(COCCOCCOC)cc3)cncc2s1 |
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| Structure | 
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