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TargetSomatostatin receptor type 2
LigandBDBM50105473
Substrate/Competitorn/a
Meas. Tech.ChEMBL_200991 (CHEMBL801242)
IC50 6500±n/a nM
Citation Hay, BACole, BMDiCapua, FMKirk, GWMurray, MCNardone, RAPelletier, DJRicketts, APRobertson, ASSiegel, TW Small molecule somatostatin receptor subtype-2 antagonists. Bioorg Med Chem Lett11:2731-4 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Somatostatin receptor type 2
Name:Somatostatin receptor type 2
Synonyms:SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2)
Type:Enzyme
Mol. Mass.:41344.94
Organism:Homo sapiens (Human)
Description:P30874
Residue:369
Sequence:
MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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BDBM50105473
n/a
NameBDBM50105473
Synonyms:(S)-2-[(S)-3-(3-Fluoro-phenyl)-2-(toluene-4-sulfonylamino)-propionylamino]-5-guanidino-pentanoic acid methyl ester | CHEMBL330248
TypeSmall organic molecule
Emp. Form.C23H30FN5O5S
Mol. Mass.507.578
SMILES[#6]-[#8]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-c1cccc(F)c1)-[#7]S(=O)(=O)c1ccc(-[#6])cc1
Structure
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