| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
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| Ligand | BDBM50105469 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_200991 (CHEMBL801242) |
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| IC50 | 6.5±n/a nM |
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| Citation |  Hay, BA; Cole, BM; DiCapua, FM; Kirk, GW; Murray, MC; Nardone, RA; Pelletier, DJ; Ricketts, AP; Robertson, AS; Siegel, TW Small molecule somatostatin receptor subtype-2 antagonists. Bioorg Med Chem Lett11:2731-4 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 2 |
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| Name: | Somatostatin receptor type 2 |
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| Synonyms: | SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41344.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30874 |
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| Residue: | 369 |
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| Sequence: | MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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| BDBM50105469 |
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| n/a |
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| Name | BDBM50105469 |
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| Synonyms: | (S)-6-Amino-2-((R)-3-(1H-indol-3-yl)-2-{[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carbonyl]-amino}-propionylamino)-hexanoic acid tert-butyl ester | CHEMBL93859 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H45N7O5 |
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| Mol. Mass. | 631.765 |
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| SMILES | CC(C)(C)OC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O |
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| Structure | 
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