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Target5-hydroxytryptamine receptor 5A
LigandBDBM34141
Substrate/Competitorn/a
Meas. Tech.ChEMBL_3597 (CHEMBL618082)
Ki>5000±n/a nM
Citation Russell, MGBaker, RJBarden, LBeer, MSBristow, LBroughton, HBKnowles, MMcAllister, GPatel, SCastro, JL N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands. J Med Chem44:3881-95 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 5A
Name:5-hydroxytryptamine receptor 5A
Synonyms:5-HT-5A | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_RAT | 5ht5a | Htr5a | REC17 | Serotonin (5-HT) receptor | Serotonin receptor 5A
Type:Enzyme Catalytic Domain
Mol. Mass.:40684.21
Organism:RAT
Description:5-HT5a HTR5A RAT::P35364
Residue:357
Sequence:
MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFG
WGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVS
PIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDIPALWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM34141
n/a
NameBDBM34141
Synonyms:CHEMBL76237 | MS-245
TypeSmall organic molecule
Emp. Form.C19H22N2O3S
Mol. Mass.358.455
SMILESCOc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1
Structure
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