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Target5-hydroxytryptamine receptor 2A
LigandBDBM34141
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2207 (CHEMBL617032)
Ki 65±n/a nM
Citation Russell, MGBaker, RJBarden, LBeer, MSBristow, LBroughton, HBKnowles, MMcAllister, GPatel, SCastro, JL N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands. J Med Chem44:3881-95 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2A
Name:5-hydroxytryptamine receptor 2A
Synonyms:5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52852.05
Organism:Rattus norvegicus (rat)
Description:Rat cortex membranes 5-HT2A receptors.
Residue:471
Sequence:
MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
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  Blast E-value cutoff:
BDBM34141
n/a
NameBDBM34141
Synonyms:CHEMBL76237 | MS-245
TypeSmall organic molecule
Emp. Form.C19H22N2O3S
Mol. Mass.358.455
SMILESCOc1ccc2n(cc(CCN(C)C)c2c1)S(=O)(=O)c1ccccc1
Structure
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