| Reaction Details |
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 | Report a problem with these data |
| Target | Insulin-like growth factor-binding protein 2 |
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| Ligand | BDBM50106431 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90402 (CHEMBL698357) |
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| Ki | 2.1±n/a nM |
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| Citation |  Chen, C; Zhu, YF; Liu, XJ; Lu, ZX; Xie, Q; Ling, N Discovery of a series of nonpeptide small molecules that inhibit the binding of insulin-like growth factor (IGF) to IGF-binding proteins. J Med Chem44:4001-10 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Insulin-like growth factor-binding protein 2 |
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| Name: | Insulin-like growth factor-binding protein 2 |
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| Synonyms: | BP2 | IBP2 | IBP2_HUMAN | IGFBP2 | Insulin-like growth factor binding protein 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34820.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_90402 |
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| Residue: | 325 |
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| Sequence: | MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPVAP
PAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYTPRCGQGLRCYPHPGSELP
LQALVMGEGTCEKRRDAEYGASPEQVADNGDDHSEGGLVENHVDSTMNMLGGGGSAGRKP
LKSGMKELAVFREKVTEQHRQMGKGGKHHLGLEEPKKLRPPPARTPCQQELDQVLERIST
MRLPDERGPLEHLYSLHIPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTI
RGDPECHLFYNEQQEARGVHTQRMQ
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| BDBM50106431 |
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| n/a |
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| Name | BDBM50106431 |
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| Synonyms: | 1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoline-3-carboxylic acid | CHEMBL292700 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H11NO7 |
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| Mol. Mass. | 341.2717 |
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| SMILES | OC(=O)c1cc2cc(O)c(O)cc2c(n1)C(=O)c1ccc(O)c(O)c1 |
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| Structure | 
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