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TargetBeta-3 adrenergic receptor
LigandBDBM50106852
Substrate/Competitorn/a
Meas. Tech.ChEBML_39053
Ki 8±n/a nM
Citation Gavai AVSher PMMikkilineni ABPoss KMMcCann PJGirotra RNFisher LGWu GBednarz MSMathur AWang TCSun CQSlusarchyk DASkwish SAllen GTHillyer DEFrohlich BHAbboa-Offei BECap MWaldron TLGeorge RJTesfamariam BHarper TWCiosek CPYoung DADickinson KESeymour AAArbeeny CMWashburn WN BMS-196085: a potent and selective full agonist of the human beta(3) adrenergic receptor. Bioorg Med Chem Lett 11:3041-4 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB3 | B3AR | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:43534.88
Organism:Homo sapiens (Human)
Description:n/a
Residue:408
Sequence:
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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  Blast E-value cutoff:
BDBM50106852
n/a
NameBDBM50106852
Synonyms:CHEMBL321518 | N-{5-[(R)-2-((R)-1-Benzo[1,3]dioxol-5-yl-2-phenyl-ethylamino)-1-hydroxy-ethyl]-2-hydroxy-phenyl}-methanesulfonamide
TypeSmall organic molecule
Emp. Form.C24H26N2O6S
Mol. Mass.470.538
SMILESCS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CN[C@H](Cc1ccccc1)c1ccc2OCOc2c1
Structure
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