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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50107195
Substrate/Competitorn/a
Meas. Tech.ChEMBL_223691 (CHEMBL846101)
Ki 2.25±n/a nM
Citation Huang, YHammond, PSWu, LMach, RH Synthesis and structure-activity relationships of N-(1-benzylpiperidin-4-yl)arylacetamide analogues as potent sigma1 receptor ligands. J Med Chem44:4404-15 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50107195
n/a
NameBDBM50107195
Synonyms:2-(3-Fluoro-phenyl)-N-[1-(4-iodo-benzyl)-piperidin-4-yl]-acetamide | CHEMBL344425
TypeSmall organic molecule
Emp. Form.C20H22FIN2O
Mol. Mass.452.3044
SMILESFc1cccc(CC(=O)NC2CCN(Cc3ccc(I)cc3)CC2)c1
Structure
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