Reaction Details |
| Report a problem with these data |
Target | Sigma non-opioid intracellular receptor 1 |
---|
Ligand | BDBM50107208 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_223691 (CHEMBL846101) |
---|
Ki | 3.93±n/a nM |
---|
Citation | Huang, Y; Hammond, PS; Wu, L; Mach, RH Synthesis and structure-activity relationships of N-(1-benzylpiperidin-4-yl)arylacetamide analogues as potent sigma1 receptor ligands. J Med Chem44:4404-15 (2001) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Sigma non-opioid intracellular receptor 1 |
---|
Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25124.85 |
Organism: | Homo sapiens (Human) |
Description: | Q99720 |
Residue: | 223 |
Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
|
|
|
BDBM50107208 |
---|
n/a |
---|
Name | BDBM50107208 |
Synonyms: | CHEMBL138688 | N-(1-Benzyl-piperidin-4-yl)-2-thiophen-2-yl-acetamide |
Type | Small organic molecule |
Emp. Form. | C18H22N2OS |
Mol. Mass. | 314.445 |
SMILES | O=C(Cc1cccs1)NC1CCN(Cc2ccccc2)CC1 |
Structure |
|