| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50107227 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_223691 (CHEMBL846101) |
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| Ki | 3.49±n/a nM |
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| Citation |  Huang, Y; Hammond, PS; Wu, L; Mach, RH Synthesis and structure-activity relationships of N-(1-benzylpiperidin-4-yl)arylacetamide analogues as potent sigma1 receptor ligands. J Med Chem44:4404-15 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50107227 |
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| n/a |
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| Name | BDBM50107227 |
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| Synonyms: | 2-(3-Bromo-phenyl)-N-[1-(3-iodo-benzyl)-piperidin-4-yl]-acetamide | CHEMBL337796 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22BrIN2O |
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| Mol. Mass. | 513.21 |
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| SMILES | Brc1cccc(CC(=O)NC2CCN(Cc3cccc(I)c3)CC2)c1 |
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| Structure | 
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