| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50108439 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_145327 |
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| IC50 | 639±n/a nM |
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| Citation |  Semple, G; Andersson, BM; Chhajlani, V; Georgsson, J; Johansson, M; Lindschoten, M; Pontén, F; Rosenquist, A; Sörensen, H; Swanson, L; Swanson, M 3-Aryl pyridone derivatives. Potent and selective kappa opioid receptor agonists. Bioorg Med Chem Lett12:197-200 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50108439 |
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| n/a |
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| Name | BDBM50108439 |
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| Synonyms: | 1-(1-Phenyl-2-pyrrolidin-1-yl-ethyl)-3-m-tolyl-1H-pyridin-2-one | CHEMBL302684 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N2O |
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| Mol. Mass. | 358.476 |
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| SMILES | Cc1cccc(c1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O |
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| Structure | 
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