| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50108447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_145604 |
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| IC50 | 3460±n/a nM |
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| Citation |  Semple, G; Andersson, BM; Chhajlani, V; Georgsson, J; Johansson, M; Lindschoten, M; Pontén, F; Rosenquist, A; Sörensen, H; Swanson, L; Swanson, M 3-Aryl pyridone derivatives. Potent and selective kappa opioid receptor agonists. Bioorg Med Chem Lett12:197-200 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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|
|
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| BDBM50108447 |
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| n/a |
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| Name | BDBM50108447 |
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| Synonyms: | 3-(5-Fluoro-2-methoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one | CHEMBL64284 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25FN2O2 |
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| Mol. Mass. | 392.4659 |
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| SMILES | COc1ccc(F)cc1-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O |
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| Structure | 
|
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