| Reaction Details |
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 | Report a problem with these data |
| Target | Kynureninase |
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| Ligand | BDBM50109155 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_91729 (CHEMBL702027) |
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| Ki | 10000±n/a nM |
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| Citation |  Walsh, HA; Leslie, PL; O'Shea, KC; Botting, NP 2-Amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic acid; a potent inhibitor of rat and recombinant human kynureninase. Bioorg Med Chem Lett12:361-3 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Kynureninase |
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| Name: | Kynureninase |
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| Synonyms: | KYNU | KYNU_HUMAN | L-kynurenine hydrolase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52356.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_91729 |
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| Residue: | 465 |
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| Sequence: | MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK
SVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEK
RGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN
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| BDBM50109155 |
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| n/a |
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| Name | BDBM50109155 |
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| Synonyms: | 2-Amino-4-hydroxy-4-(3-hydroxy-phenyl)-butyric acid | 2-amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic acid | CHEMBL120534 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H13NO4 |
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| Mol. Mass. | 211.2145 |
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| SMILES | NC(CC(O)c1cccc(O)c1)C(O)=O |
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| Structure | 
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