Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50109384 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_201564 |
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Ki | 4.2±n/a nM |
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Citation | Maeda, DY; Williams, W; Kim, WE; Thatcher, LN; Bowen, WD; Coop, A N-arylalkylpiperidines as high-affinity sigma-1 and sigma-2 receptor ligands: phenylpropylamines as potential leads for selective sigma-2 agents. Bioorg Med Chem Lett12:497-500 (2002) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50109384 |
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n/a |
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Name | BDBM50109384 |
Synonyms: | 3-Methyl-1-phenethyl-piperidine | CHEMBL144552 |
Type | Small organic molecule |
Emp. Form. | C14H21N |
Mol. Mass. | 203.3232 |
SMILES | CC1CCCN(CCc2ccccc2)C1 |
Structure |
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