| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase/RNaseH |
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| Ligand | BDBM50109690 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195678 (CHEMBL800750) |
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| IC50 | 7900±n/a nM |
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| Citation |  Tillekeratne, LM; Sherette, A; Fulmer, JA; Hupe, L; Hupe, D; Gabbara, S; Peliska, JA; Hudson, RA Differential inhibition of polymerase and strand-transfer activities of HIV-1 reverse transcriptase. Bioorg Med Chem Lett12:525-8 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase/RNaseH |
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| Name: | Reverse transcriptase/RNaseH |
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| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH |
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| Type: | PROTEIN |
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| Mol. Mass.: | 65229.15 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_1473730 |
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| Residue: | 566 |
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| Sequence: | PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRQLCKLLRGTKALTEVIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLRTGKYARMRGA
HTNDVKQLTEAVQKITTESIVIWGKTPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTNRGRQKVVTLTDTTNQKTELQ
AIYLALQDSGLEVNIVTDSQYALGIIQAQPDQSESELVNQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSAGIRKVLFLDGID
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| BDBM50109690 |
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| n/a |
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| Name | BDBM50109690 |
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| Synonyms: | 3,4,5-Trihydroxy-benzoic acid 2-(4-hydroxy-phenyl)-ethyl ester | 4-hydroxyphenethyl 3,4,5-trihydroxybenzoate | CHEMBL147069 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14O6 |
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| Mol. Mass. | 290.2681 |
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| SMILES | Oc1ccc(CCOC(=O)c2cc(O)c(O)c(O)c2)cc1 |
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| Structure | 
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