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TargetCalcitonin receptor
LigandBDBM50110275
Substrate/Competitorn/a
Meas. Tech.ChEMBL_42610
Ki 0.069000±n/a nM
Citation Taylor JWJin QKSbacchi MWang LBelfiore PGarnier MKazantzis AKapurniotu AZaratin PFScheideler MA Side-chain lactam-bridge conformational constraints differentiate the activities of salmon and human calcitonins and reveal a new design concept for potent calcitonin analogues. J Med Chem 45:1108-21 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Calcitonin receptor
Name:Calcitonin receptor
Synonyms:CALCR | CT-R
Type:PROTEIN
Mol. Mass.:59372.80
Organism:Homo sapiens (Human)
Description:ChEMBL_42610
Residue:508
Sequence:
MQFSGEKISGQRDLQKSKMRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYV
VGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDF
DPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFT
LVISLGIFVFFRKLTTIFPLNWKYRKALSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVV
PNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLG
WGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTK
MRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFF
VATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQE
PRNEPANNQGEESAEIIPLNIIEQESSA
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  Blast E-value cutoff:
BDBM50110275
n/a
NameBDBM50110275
Synonyms:CGNLSTCBLGTYTQDF[DKFHO]YPQTAIGVGAP-amide | CHEMBL2369915
TypeSmall organic molecule
Emp. Form.C146H244N44O47S2
Mol. Mass.3431.896
SMILESn/a
Structure
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