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TargetCalcitonin receptor
LigandBDBM50110275
Substrate/Competitorn/a
Meas. Tech.ChEMBL_42740
IC50 0.408000±n/a nM
Citation Taylor JWJin QKSbacchi MWang LBelfiore PGarnier MKazantzis AKapurniotu AZaratin PFScheideler MA Side-chain lactam-bridge conformational constraints differentiate the activities of salmon and human calcitonins and reveal a new design concept for potent calcitonin analogues. J Med Chem 45:1108-21 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Calcitonin receptor
Name:Calcitonin receptor
Synonyms:C1A/C1B | CT-R
Type:PROTEIN
Mol. Mass.:60302.08
Organism:Rattus norvegicus
Description:ChEMBL_42740
Residue:516
Sequence:
MRFLLLNRFTLLLLLLVSPTPVLQAPTNLTDSGLDQEPFLYLVGRKKLLDAQYKCYDRIQ
QLPPYEGEGPYCNRTWDGWMCWDDTPAGVMSYQHCPDYFPDFDPTEKVSKYCDENGEWFR
HPDSNRTWSNYTLCNAFTPDKLHNAYVLYYLALVGHSMSIAALIASMGIFLFFKNLSCQR
VTLHKNMFLTYILNSIIIIIHLVEVVPNGDLVRRDPMHIFHHNTYMWTMQWELSPPLPLS
AHEGKMDPHDSEVISCKILHFFHQYMMACNYFWMLCEGIYLHTLIVMAVFTEDQRLRWYY
LLGWGFPIVPTIIHAITRAVYYNDNCWLSTETHLLYIIHGPVMAALVVNFFFLLNIVRVL
VTKMRQTHEAEAYMYLKAVKATMVLVPLLGIQFVVFPWRPSNKVLGKIYDYLMHSLIHFQ
GFFVATIYCFCNHEVQVTLKRQWAQFKIQWSHRWGRRRRPTNRVVSAPRAVAFAEPGGLP
IYICHQEPRNPPVSNNEGEEGTEMIPMNVIQQDSSA
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  Blast E-value cutoff:
BDBM50110275
n/a
NameBDBM50110275
Synonyms:CGNLSTCBLGTYTQDF[DKFHO]YPQTAIGVGAP-amide | CHEMBL2369915
TypeSmall organic molecule
Emp. Form.C146H244N44O47S2
Mol. Mass.3431.896
SMILESn/a
Structure
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