| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine N-methyltransferase |
|---|
| Ligand | BDBM50110304 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_87238 (CHEMBL696458) |
|---|
| IC50 | 140±n/a nM |
|---|
| Citation |  Apelt, J; Ligneau, X; Pertz, HH; Arrang, JM; Ganellin, CR; Schwartz, JC; Schunack, W; Stark, H Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity. J Med Chem45:1128-41 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine N-methyltransferase |
|---|
| Name: | Histamine N-methyltransferase |
|---|
| Synonyms: | HNMT_RAT | Hnmt |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 33931.03 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_87236 |
|---|
| Residue: | 295 |
|---|
| Sequence: | MASFMRSLFSDHSRYVESFRRFLNNSTEHQCMQEFMDKKLPGIIARIGETKAEIKILSIG
GGAGEIDLQILSKVQAQYPGICINNEVVEPNAEQIVKYKELVAKTSNMENIKFAWHKETS
SEYQKRVVEEDEEPPKWDFIHMIQMLYYVKDIPATLKFFHGLLAANAKILIILVSGTSGW
EKLWKKYGFRLPRDDLCQYVTSSDLAQILDDLGIKYECYDLLSTMDITDCFIDGNENGDL
LWDFLTETCNFIKTAPLDLKEEIMKDLQEPEFSVKKEGKVLFNNNLSFIVVEANV
|
|
|
|---|
| BDBM50110304 |
|---|
| n/a |
|---|
| Name | BDBM50110304 |
|---|
| Synonyms: | (7-Chloro-quinolin-4-yl)-(5-piperidin-1-yl-pentyl)-amine; Oxalic acid | CHEMBL14816 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H26ClN3 |
|---|
| Mol. Mass. | 331.883 |
|---|
| SMILES | Clc1ccc2c(NCCCCCN3CCCCC3)ccnc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
