| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase Fyn |
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| Ligand | BDBM50111434 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_69438 |
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| IC50 | >250000±n/a nM |
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| Citation |  Song, Y; Wang, J; Teng, SF; Kesuma, D; Deng, Y; Duan, J; Wang, JH; Qi, RZ; Sim, MM Beta-carbolines as specific inhibitors of cyclin-dependent kinases. Bioorg Med Chem Lett12:1129-32 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase Fyn |
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| Name: | Tyrosine-protein kinase Fyn |
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| Synonyms: | FYN | FYN_HUMAN | Proto-oncogene Syn | Proto-oncogene c-Fyn | SLK | SRC | Src-like kinase | p59-Fyn |
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| Type: | Enzyme |
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| Mol. Mass.: | 60762.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06241 |
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| Residue: | 537 |
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| Sequence: | MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQG
LTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWW
EARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESET
TKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCC
RLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKT
LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGR
ALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE
RGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL
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| BDBM50111434 |
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| n/a |
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| Name | BDBM50111434 |
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| Synonyms: | 1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | CHEMBL273547 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N4 |
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| Mol. Mass. | 248.2826 |
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| SMILES | Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12 |
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| Structure | 
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