| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein kinase Fyn |
|---|
| Ligand | BDBM50111435 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_69438 |
|---|
| IC50 | >250000±n/a nM |
|---|
| Citation |  Song, Y; Wang, J; Teng, SF; Kesuma, D; Deng, Y; Duan, J; Wang, JH; Qi, RZ; Sim, MM Beta-carbolines as specific inhibitors of cyclin-dependent kinases. Bioorg Med Chem Lett12:1129-32 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosine-protein kinase Fyn |
|---|
| Name: | Tyrosine-protein kinase Fyn |
|---|
| Synonyms: | FYN | FYN_HUMAN | Proto-oncogene Syn | Proto-oncogene c-Fyn | SLK | SRC | Src-like kinase | p59-Fyn |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 60762.21 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P06241 |
|---|
| Residue: | 537 |
|---|
| Sequence: | MGCVQCKDKEATKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQG
LTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWW
EARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESET
TKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCC
RLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKT
LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKDGEGR
ALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE
RGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQSFLEDYFTATEPQYQPGENL
|
|
|
|---|
| BDBM50111435 |
|---|
| n/a |
|---|
| Name | BDBM50111435 |
|---|
| Synonyms: | 7-Fluoro-1-methyl-9H-beta-carboline | CHEMBL14445 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H9FN2 |
|---|
| Mol. Mass. | 200.2117 |
|---|
| SMILES | Cc1nccc2c3ccc(F)cc3[nH]c12 |
|---|
| Structure | 
|
|---|
Search and Browse
