| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50111627 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_139066 (CHEMBL745661) |
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| Ki | 500±n/a nM |
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| Citation |  Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Synthesis and pharmacological evaluation of 6-piperidino- and 6-piperazinoalkyl-2(3H)-benzothiazolones as mixed sigma/5-HT(1A) ligands. Bioorg Med Chem Lett12:1149-52 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_RAT | Cholinergic, muscarinic M1 | Chrm-1 | Chrm1 | cholinergic receptor, muscarinic 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51390.46 |
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| Organism: | RAT |
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| Description: | P08482 |
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| Residue: | 460 |
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| Sequence: | MNTSVPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPESPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDSEAQAPTKQPPKSSPNTVKRPTKKGRDRGGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTVNPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50111627 |
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| n/a |
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| Name | BDBM50111627 |
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| Synonyms: | 6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-benzothiazol-2-one | CHEMBL15955 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N3OS |
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| Mol. Mass. | 367.508 |
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| SMILES | Cn1c2ccc(CCN3CCN(Cc4ccccc4)CC3)cc2sc1=O |
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| Structure | 
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