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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50111632
Substrate/Competitorn/a
Meas. Tech.ChEBML_201567
Ki 3±n/a nM
Citation Mouithys-Mickalad, APoupaert, JHSpampinato, SLesieur, D Synthesis and pharmacological evaluation of 6-piperidino- and 6-piperazinoalkyl-2(3H)-benzothiazolones as mixed sigma/5-HT(1A) ligands. Bioorg Med Chem Lett12:1149-52 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma non-opioid intracellular receptor 1
Synonyms:Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50111632
n/a
NameBDBM50111632
Synonyms:3-Methyl-6-[4-(4-phenyl-piperidin-1-yl)-butyl]-3H-benzothiazol-2-one | CHEMBL15986
TypeSmall organic molecule
Emp. Form.C23H28N2OS
Mol. Mass.380.546
SMILESCn1c2ccc(CCCCN3CCC(CC3)c3ccccc3)cc2sc1=O
Structure
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