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Reaction Details
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TargetAdenosine receptor A1
LigandBDBM50112196
Substrate/Competitorn/a
Meas. Tech.ChEMBL_29011 (CHEMBL643485)
Ki 473.0±n/a nM
Citation Van Calenbergh, SLink, AFujikawa, Sde Ligt, RAVanheusden, VGolisade, ABlaton, NMRozenski, JIJzerman, APHerdewijn, P 5'-Deoxy congeners of 9-(3-amido-3-deoxy-beta-D-xylofuranosyl)-N(6)-cyclopentyladenine: new adenosine A(1) receptor antagonists and inverse agonists. J Med Chem45:1845-52 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor A1
Synonyms:AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:Protein
Mol. Mass.:36704.13
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50112196
n/a
NameBDBM50112196
Synonyms:CHEMBL301116 | N-[5-(6-Cyclopentylamino-purin-9-yl)-4-hydroxy-2-methyl-tetrahydro-furan-3-yl]-4-phenoxy-butyramide
TypeSmall organic molecule
Emp. Form.C25H32N6O4
Mol. Mass.480.5594
SMILESC[C@H]1O[C@H]([C@H](O)[C@H]1NC(=O)CCCOc1ccccc1)n1cnc2c(NC3CCCC3)ncnc12
Structure
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