| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor |
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| Ligand | BDBM50112202 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105404 |
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| Ki | 0.770000±n/a nM |
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| Citation |  Leclerc V; Yous S; Delagrange P; Boutin JA; Renard P; Lesieur D Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3). J Med Chem 45:1853-9 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor |
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| Name: | Melatonin receptor |
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| Synonyms: | MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50112202 |
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| n/a |
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| Name | BDBM50112202 |
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| Synonyms: | CHEMBL55084 | N-[2-(2-Iodo-5-methoxy-1-methyl-6-nitro-1H-indol-3-yl)-ethyl]-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16IN3O4 |
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| Mol. Mass. | 417.199 |
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| SMILES | COc1cc2c(CCNC(C)=O)c(I)n(C)c2cc1[N+]([O-])=O |
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| Structure | 
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