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TargetMelatonin receptor
LigandBDBM50112204
Substrate/Competitorn/a
Meas. Tech.ChEMBL_104950
Ki 0.300000±n/a nM
Citation Leclerc VYous SDelagrange PBoutin JARenard PLesieur D Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3). J Med Chem 45:1853-9 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50112204
n/a
NameBDBM50112204
Synonyms:CHEMBL52755 | N-[2-(2-Iodo-5-methoxy-6-nitro-1H-indol-3-yl)-ethyl]-acetamide
TypeSmall organic molecule
Emp. Form.C13H14IN3O4
Mol. Mass.403.1724
SMILESCOc1cc2c(CCNC(C)=O)c(I)[nH]c2cc1[N+]([O-])=O
Structure
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