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TargetMelatonin receptor
LigandBDBM50112201
Substrate/Competitorn/a
Meas. Tech.ChEMBL_104950
Ki 8560.0±n/a nM
Citation Leclerc VYous SDelagrange PBoutin JARenard PLesieur D Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3). J Med Chem 45:1853-9 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50112201
n/a
NameBDBM50112201
Synonyms:CHEMBL53622 | N-(2-(5-methoxy-1-methyl-4-nitro-1H-indol-3-yl)ethyl)acetamide | N-[2-(5-Methoxy-1-methyl-4-nitro-1H-indol-3-yl)-ethyl]-acetamide
TypeSmall organic molecule
Emp. Form.C14H17N3O4
Mol. Mass.291.3025
SMILESCOc1ccc2n(C)cc(CCNC(C)=O)c2c1[N+]([O-])=O
Structure
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