| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin-releasing peptide receptor |
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| Ligand | BDBM50112616 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_39620 (CHEMBL649928) |
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| IC50 | 20.5±n/a nM |
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| Citation |  Achilefu, S; Jimenez, HN; Dorshow, RB; Bugaj, JE; Webb, EG; Wilhelm, RR; Rajagopalan, R; Johler, J; Erion, JL Synthesis, in vitro receptor binding, and in vivo evaluation of fluorescein and carbocyanine peptide-based optical contrast agents. J Med Chem45:2003-15 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin-releasing peptide receptor |
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| Name: | Gastrin-releasing peptide receptor |
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| Synonyms: | GRPR_RAT | Gastrin-Releasing peptide | Gastrin-releasing peptide receptor | Grpr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43227.55 |
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| Organism: | RAT |
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| Description: | Gastrin-Releasing peptide 0 RAT::P52500 |
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| Residue: | 384 |
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| Sequence: | MDPNNCSHLNLEVDPFLSCNNTFNQTLSPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNI
TLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFI
QLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFS
DLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQ
SAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSML
HFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMT
SFKSTNPSATFSLINGNICHEGYV
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| BDBM50112616 |
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| n/a |
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| Name | BDBM50112616 |
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| Synonyms: | (alpha,epsilon-(FITC)2-K-G-S-G-Q-W-A-V-G-H-L-M-NH2) | CHEMBL438179 |
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| Type | Small organic molecule |
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| Emp. Form. | C98H110N20O24S3 |
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| Mol. Mass. | 2048.237 |
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| SMILES | CSCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CCC(N)=O)NC(=O)CNC(=O)C(CO)NC(=O)CNC(=O)C(CCCCNC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)NC(=S)Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)C(C)C)C(N)=O |
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| Structure | 
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