| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50114730 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105099 (CHEMBL714106) |
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| Ki | 0.75±n/a nM |
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| Citation |  Wallez, V; Durieux-Poissonnier, S; Chavatte, P; Boutin, JA; Audinot, V; Nicolas, JP; Bennejean, C; Delagrange, P; Renard, P; Lesieur, D Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands. J Med Chem45:2788-800 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50114730 |
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| n/a |
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| Name | BDBM50114730 |
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| Synonyms: | CHEMBL95166 | N-{2-[2-(3-Fluoro-benzyl)-5-methoxy-benzofuran-3-yl]-ethyl}-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20FNO3 |
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| Mol. Mass. | 341.3761 |
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| SMILES | COc1ccc2oc(Cc3cccc(F)c3)c(CCNC(C)=O)c2c1 |
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| Structure | 
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