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TargetMelatonin receptor type 1A
LigandBDBM50114732
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105099 (CHEMBL714106)
Ki 0.04±n/a nM
Citation Wallez, VDurieux-Poissonnier, SChavatte, PBoutin, JAAudinot, VNicolas, JPBennejean, CDelagrange, PRenard, PLesieur, D Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands. J Med Chem45:2788-800 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor type 1A
Name:Melatonin receptor type 1A
Synonyms:MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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  Blast E-value cutoff:
BDBM50114732
n/a
NameBDBM50114732
Synonyms:1-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-3-methyl-urea | CHEMBL94838
TypeSmall organic molecule
Emp. Form.C19H20N2O3
Mol. Mass.324.3737
SMILESCNC(=O)NCCc1c(oc2ccc(OC)cc12)-c1ccccc1
Structure
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