Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMelatonin receptor type 1B
LigandBDBM50114725
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105263 (CHEMBL715855)
Ki 0.01±n/a nM
Citation Wallez, VDurieux-Poissonnier, SChavatte, PBoutin, JAAudinot, VNicolas, JPBennejean, CDelagrange, PRenard, PLesieur, D Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands. J Med Chem45:2788-800 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor type 1B
Name:Melatonin receptor type 1B
Synonyms:MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50114725
n/a
NameBDBM50114725
Synonyms:CHEMBL314512 | N-[2-(5-Methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-acrylamide
TypeSmall organic molecule
Emp. Form.C20H19NO3
Mol. Mass.321.3698
SMILESCOc1ccc2oc(c(CCNC(=O)C=C)c2c1)-c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: