| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50115292 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_104587 (CHEMBL715332) |
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| IC50 | 0.790000±n/a nM |
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| Citation |  Cheng, Z; Chen, J; Miao, Y; Owen, NK; Quinn, TP; Jurisson, SS Modification of the structure of a metallopeptide: synthesis and biological evaluation of (111)In-labeled DOTA-conjugated rhenium-cyclized alpha-MSH analogues. J Med Chem45:3048-56 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35238.60 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498846 |
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| Residue: | 315 |
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| Sequence: | MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
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| BDBM50115292 |
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| n/a |
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| Name | BDBM50115292 |
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| Synonyms: | CHEMBL438180 | DOTA-ReCCEHdFRWCKPVD-OH |
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| Type | Small organic molecule |
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| Emp. Form. | C79H111N25O25ReS3 |
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| Mol. Mass. | 2093.282 |
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| SMILES | CC(C)C(NC(=O)C1CCCN1C(=O)C(CCCNC(N)=N)NC(=O)C1NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)C(Cc2cnc[nH]2)NC(=O)C(CCC(O)=O)NC(=O)C2S[Re-]3([O-])(SC(NC(=O)CN4CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC4)C(=O)N23)S1)C(=O)NC(CC(O)=O)C(O)=O |
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| Structure | 
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