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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin releasing factor receptor 1 | ||
| Ligand | BDBM50116112 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_51124 | ||
| Ki | 1±n/a nM | ||
| Citation |  Yuan J; Gulianello M; De Lombaert S; Brodbeck R; Kieltyka A; Hodgetts KJ 3-Aryl pyrazolo[4,3-d]pyrimidine derivatives: Nonpeptide CRF-1 antagonists. Bioorg Med Chem Lett 12:2133-6 (2002) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin releasing factor receptor 1 | |||
| Name: | Corticotropin releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRH-R 1 | CRHR1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM50116112 | |||
| n/a | |||
| Name | BDBM50116112 | ||
| Synonyms: | CHEMBL67484 | [1,5-Dimethyl-3-(2,4,6-trimethyl-phenyl)-1H-pyrazolo[4,3-d]pyrimidin-7-yl]-dipropyl-amine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H31N5 | ||
| Mol. Mass. | 365.515 | ||
| SMILES | CCCN(CCC)c1nc(C)nc2c(nn(C)c12)-c1c(C)cc(C)cc1C |(-6.92,3.47,;-5.59,2.68,;-5.62,1.14,;-4.31,.34,;-2.96,1.09,;-2.93,2.63,;-1.58,3.36,;-4.33,-1.2,;-5.69,-1.94,;-5.73,-3.48,;-7.07,-4.23,;-4.4,-4.28,;-3.05,-3.53,;-1.59,-4.04,;-.65,-2.81,;-1.54,-1.54,;-1.04,-.08,;-3.03,-1.99,;-1.14,-5.51,;.36,-5.84,;1.4,-4.71,;.82,-7.31,;-.25,-8.45,;.22,-9.92,;-1.74,-8.1,;-2.19,-6.63,;-3.69,-6.28,)| | ||
| Structure | 
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