| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50116382 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_31694 (CHEMBL876574) |
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| Ki | 6.3±n/a nM |
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| Citation |  Priego, EM; von Frijtag Drabbe Kuenzel, J; IJzerman, AP; Camarasa, MJ; Pérez-Pérez, MJ Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists. J Med Chem45:3337-44 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50116382 |
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| n/a |
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| Name | BDBM50116382 |
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| Synonyms: | 1-Benzyl-3-isobutyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione | CHEMBL323717 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N4O2 |
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| Mol. Mass. | 348.3984 |
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| SMILES | CC(C)Cn1c(=O)n(Cc2ccccc2)c2nc3ccccn3c2c1=O |
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| Structure | 
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