| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
|---|
| Ligand | BDBM50116608 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_143678 (CHEMBL755166) |
|---|
| IC50 | 8±n/a nM |
|---|
| Citation |  Block, MH; Boyer, S; Brailsford, W; Brittain, DR; Carroll, D; Chapman, S; Clarke, DS; Donald, CS; Foote, KM; Godfrey, L; Ladner, A; Marsham, PR; Masters, DJ; Mee, CD; O'Donovan, MR; Pease, JE; Pickup, AG; Rayner, JW; Roberts, A; Schofield, P; Suleman, A; Turnbull, AV Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity. J Med Chem45:3509-23 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuropeptide Y receptor type 5 |
|---|
| Name: | Neuropeptide Y receptor type 5 |
|---|
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 50746.64 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q15761 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
|
|
|
|---|
| BDBM50116608 |
|---|
| n/a |
|---|
| Name | BDBM50116608 |
|---|
| Synonyms: | CHEMBL117922 | N-(9-Dimethylsulfamoyl-9H-carbazol-3-yl)-3-pyridin-4-yl-propionamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H22N4O3S |
|---|
| Mol. Mass. | 422.5 |
|---|
| SMILES | CN(C)S(=O)(=O)n1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
