| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
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| Ligand | BDBM50116600 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143682 (CHEMBL756249) |
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| IC50 | 7±n/a nM |
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| Citation |  Block, MH; Boyer, S; Brailsford, W; Brittain, DR; Carroll, D; Chapman, S; Clarke, DS; Donald, CS; Foote, KM; Godfrey, L; Ladner, A; Marsham, PR; Masters, DJ; Mee, CD; O'Donovan, MR; Pease, JE; Pickup, AG; Rayner, JW; Roberts, A; Schofield, P; Suleman, A; Turnbull, AV Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity. J Med Chem45:3509-23 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 5 |
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| Name: | Neuropeptide Y receptor type 5 |
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| Synonyms: | NPY-Y5 | NPY5R_RAT | Neuropeptide Y receptor type 5 | Npy5r | Npyr5 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50435.58 |
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| Organism: | Rat 6B |
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| Description: | NPY-Y5 NPY5R Rat 6B::Q63634 |
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| Residue: | 445 |
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| Sequence: | MEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNL
LILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAP
AGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKK
RSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLN
PILYGFLNNGIKADLRALIHCLHMS
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| BDBM50116600 |
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| n/a |
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| Name | BDBM50116600 |
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| Synonyms: | CHEMBL325475 | N-(9-Ethyl-9H-carbazol-3-yl)-3-pyridin-4-yl-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N3O |
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| Mol. Mass. | 343.4216 |
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| SMILES | CCn1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc12 |
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| Structure | 
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