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TargetPeptidyl-prolyl cis-trans isomerase FKBP1A
LigandBDBM50116631
Substrate/Competitorn/a
Meas. Tech.ChEMBL_66275 (CHEMBL678145)
Ki 11±n/a nM
Citation Hamilton, GSWu, YQLimburg, DCWilkinson, DEVaal, MJLi, JHThomas, CHuang, WSauer, HRoss, DTSoni, RChen, YGuo, HHoworth, PValentine, HLiang, SSpicer, DFuller, MSteiner, JP Synthesis of N-glyoxyl prolyl and pipecolyl amides and thioesters and evaluation of their in vitro and in vivo nerve regenerative effects. J Med Chem45:3549-57 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Peptidyl-prolyl cis-trans isomerase FKBP1A
Name:Peptidyl-prolyl cis-trans isomerase FKBP1A
Synonyms:12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B
Type:Isomerase
Mol. Mass.:11953.09
Organism:Homo sapiens (Human)
Description:P62942
Residue:108
Sequence:
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW
EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50116631
n/a
NameBDBM50116631
Synonyms:1-(3,3-Dimethyl-2-oxo-pentanoyl)-pyrrolidine-2-carbothioic acid S-(3-phenyl-propyl) ester | CHEMBL119228
TypeSmall organic molecule
Emp. Form.C21H29NO3S
Mol. Mass.375.525
SMILESCCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)SCCCc1ccccc1
Structure
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