| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM50116659 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_145839 |
|---|
| Ki | 5.7±n/a nM |
|---|
| Citation |  Mou, QY; Chen, J; Zhu, YC; Zhou, DH; Chi, ZQ; Long, YQ 3-Pyrroline containing arylacetamides: a novel series of remarkably selective kappa-agonists. Bioorg Med Chem Lett12:2287-90 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42692.90 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P34975 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
|
|
|
|---|
| BDBM50116659 |
|---|
| n/a |
|---|
| Name | BDBM50116659 |
|---|
| Synonyms: | 2-(3,4-Dichloro-phenyl)-N-[(S)-1-(2,5-dihydro-pyrrol-1-ylmethyl)-2-methyl-propyl]-N-methyl-acetamide | CHEMBL75831 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H24Cl2N2O |
|---|
| Mol. Mass. | 355.302 |
|---|
| SMILES | CC(C)[C@@H](CN1CC=CC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 |c:7| |
|---|
| Structure | 
|
|---|
Search and Browse
