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TargetMycothiol S-conjugate amidase
LigandBDBM50117078
Substrate/Competitorn/a
Meas. Tech.ChEBML_140808
IC50 35000±n/a nM
Citation Nicholas, GMEckman, LLRay, SHughes, ROPfefferkorn, JABarluenga, SNicolaou, KCBewley, CA Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorg Med Chem Lett12:2487-90 (2002) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Mycothiol S-conjugate amidase
Name:Mycothiol S-conjugate amidase
Synonyms:MCA_MYCTU | mca
Type:PROTEIN
Mol. Mass.:32719.79
Organism:Mycobacterium tuberculosis
Description:ChEMBL_626858
Residue:288
Sequence:
MSELRLMAVHAHPDDESSKGAATLARYADEGHRVLVVTLTGGERGEILNPAMDLPDVHGR
IAEIRRDEMTKAAEILGVEHTWLGFVDSGLPKGDLPPPLPDDCFARVPLEVSTEALVRVV
REFRPHVMTTYDENGGYPHPDHIRCHQVSVAAYEAAGDFCRFPDAGEPWTVSKLYYVHGF
LRERMQMLQDEFARHGQRGPFEQWLAYWDPDHDFLTSRVTTRVECSKYFSQRDDALRAHA
TQIDPNAEFFAAPLAWQERLWPTEEFELARSRIPARPPETELFAGIEP
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  Blast E-value cutoff:
BDBM50117078
n/a
NameBDBM50117078
Synonyms:CHEMBL197081 | CHEMBL312123 | N-[2-(4-Amino-phenyldisulfanyl)-ethyl]-3-(3-chloro-4-hydroxy-phenyl)-2-[(Z)-hydroxyimino]-propionamide
TypeSmall organic molecule
Emp. Form.C17H18ClN3O3S2
Mol. Mass.411.926
SMILESNc1ccc(SSCCNC(=O)C(Cc2ccc(O)c(Cl)c2)N=O)cc1
Structure
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