| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathionylspermidine synthase |
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| Ligand | BDBM50117546 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_72740 (CHEMBL681927) |
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| IC50 | >2000±n/a nM |
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| Citation |  Amssoms, K; Oza, SL; Ravaschino, E; Yamani, A; Lambeir, A; Rajan, P; Bal, G; Rodriguez, J; Fairlamb, AH; Augustyns, K; Haemers, A Glutathione-like tripeptides as inhibitors of glutathionylspermidine synthetase. Part 1: Substitution of the glycine carboxylic acid group. Bioorg Med Chem Lett12:2553-6 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathionylspermidine synthase |
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| Name: | Glutathionylspermidine synthase |
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| Synonyms: | GSP | GSP_CRIFA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 80299.94 |
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| Organism: | Crithidia fasciculata |
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| Description: | ChEMBL_72759 |
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| Residue: | 719 |
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| Sequence: | MSSLPHNHHYETHHRGTAEVPFDELIGVTPDGVPVISNGNEAHFSNLESITAACLPLSSF
ERKAPCKQPYRKMGVKWQCVEFVRRYLASRKAVWMTSLCTAEEVWREENLFVDVRDGRPV
EVVRTPNKSTGPAPAVADIVVWGEGPETPFGHVAIVTEVCASCVRVAEQNQGFEKWPEDV
PFSREIAMRTTESGEVELLDEDPLLGWVTVQAPFYNFDDGDLADSFRLVVGQGQILRQPF
PKHVDVPWLNTGEECDTILKHSLVVDGNMGEGAHAEEGDVPGAFYFLDYDMFCRLGRAAS
SLHRIAMAATAKVLEDPESTHLLEHYFGVPPEIQPLLRRSWEMTPPMGGRFDFGYDGKNV
VMLEYNCDSSGALLECCNTQEKMARFYGVSQGTSTGSFLGAKCVTYFQRLLTNEKVCPQH
RLIHFMIDEDDEERYTARCMMGFAEQAGFRTKLCVKLVNFRYRDGPPSNAAPLATPCDHP
TIVDGEDEEVLMVWKTWSWDTVLHQYHSQRSSSDAVNTPTLSDILLNNNIRVLEPLWKAV
TGSKAILPFMHALAPDHEHMLAASFLPTREIISRHYISKPVNGRAGQNIMMYDPVTSPTE
LEGAPQQDICEALSQNASARSLLNGSPLPLSQSVDQTNECSPGKFFDSVLVYQQRLFLKK
FDGKYFPIFCGWMVGDEFGGVVVREDTSKITKLSSMVVPARVVRDNVPLGVSYSDEGET
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| BDBM50117546 |
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| n/a |
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| Name | BDBM50117546 |
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| Synonyms: | 2-Amino-4-[1-(carbamoylmethyl-carbamoyl)-3-methyl-butylcarbamoyl]-butyric acid | CHEMBL315249 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H24N4O5 |
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| Mol. Mass. | 316.3535 |
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| SMILES | CC(C)C[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(N)=O |
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| Structure | 
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